Brian Levine, M.D.

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Brian Levine, M.D.

Brian Levine, M.D.

Associate Chief Academic Officer and Designated Institutional Official

Expertise & Research Interests

  • Antibiotic Stewardship
  • Undergraduate Medical Education
  • Emergency Medicine
  • Graduate Medical Education
  • Aeromedical Transport


  • B.A., Drew University
  • M.D., University of Vermont
  • Residency, EM, Medical Center of Delaware

Brian Levine, M.D.

Associate Chief Academic Officer and Designated Institutional Official

Brian Levine, an emergency doctor by training, is the associate chief academic officer and the designated institutional officer at ChristianaCare.

Dr. Levine oversees more than 30 residency and fellowship programs at ChristianaCare and has spearheaded ChristianaCare’s significant authorship in the development of pocket-sized reference guides used globally by thousands of emergency residents each year. The guides, published by the Emergency Medicine Residents’ Association, provide guidance on antibiotic use, the treatment of orthopaedic injuries and administering EKGs, among other issues.


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Downloadable Images and Links
Media Appearances

ACEP Frontline: Antibiotic Education (2016)

2024-06-12 , ACEP Frontline - Emergency Medicine
Host Ryan Stanton, MD, FACEP talks to Brian Levine, MD, FACEP on the development of the EMRA Antibiotic Guide, the overuse of antibiotics across medicine, and antibiotic education for physicians,PAs, and patients. Get the EMRA Antibiotic Guide on the ACEP Bookstore.

ACEP Frontline: EMRA Antibiotic Guide (2018)

2024-06-12 , ACEP Frontline - Emergency Medicine
ACEP18 has just started and we already have experts “On the Air”! Today, ACEP Frontline host Dr. Ryan Stanton and his guest Dr. Brian Levine discuss antibiotic stewardship. EMRA has just released a new antibiotic guide and it has everything you need to know! This is one conversation you don't want to miss!

EMRA Cast: Antibiotic Stewardship (2019)

2019-03-15 , EMRA Antibiotic Guide
In this episode, Dr. Jessie Werner talks to Dr. Brian Levine about the EMRA Antibiotic Guide and how it can improve your practice.
Selected Papers and Publications

Visual outcomes after traumatic retrobulbar hemorrhage are not related to time or intraocular pressure

American Journal of Emergency Medicine
The paucity of literature regarding the role of time and intraocular pressure (IOP) when treating ocular compartment syndrome (OCS) has resulted in limited guidance for emergency physicians (EP). Objectives: Our goals were to investigate the ideal time frame for lateral canthotomy, to understand the relationship between IOP and visual outcome, and to determine the impact of EP performance on visual acuity (VA).

An Evaluation of the Incidence of Nephrotoxicity After a Loading Dose of Vancomycin in Patients With Severe Renal Impairment

Journal of Emergency Medicine
Background: Loading doses of vancomycin assist in the rapid achievement of target trough concentrations. Patients with renal dysfunction have been excluded from studies evaluating loading doses. Objective: The purpose of this study was to investigate nephrotoxicity related to initial vancomycin dose in patients with severe renal dysfunction.

Immediate Stress Echocardiography for Low-Risk Chest Pain Patients in the Emergency Department: A Prospective Observational Cohort Study

Journal of Emergency Medicine
Background: Evaluation and disposition of low-risk chest pain (CP) patients in the emergency department (ED) is time consuming and expensive. Low-risk CP often results in hospital admission to rule out myocardial infarction, which leads to additional costs and delays. Objective: Our aim was to assess whether an immediate exercise stress echocardiogram (IESE) in the ED will allow safe, efficient, and cost-effective evaluation and discharge of patients with low-risk CP. Methods: Low-risk CP patients (TIMI [Thrombolysis in Myocardial Infarction] score 0-1) presenting to the ED with normal electrocardiogram, no history of coronary artery disease, and negative troponin T received IESE.

High Single-dose Vancomycin Loading Is Not Associated With Increased Nephrotoxicity in Emergency Department Sepsis Patients

Academic Emergency Medicine
Objective: Vancomycin loading doses are recommended, however, the risk of nephrotoxicity with these doses is unknown. The primary objective of this study was to compare nephrotoxicity in emergency department (ED) sepsis patients who received vancomycin at high doses (>20 mg/kg) versus lower doses (≤20 mg/kg).

Predictors of a Top Performer During Emergency Medicine Residency

Journal of Emergency Medicine
Emergency Medicine (EM) residency program directors and faculty spend significant time and effort creating a residency rank list. To date, however, there have been few studies to assist program directors in determining which pre-residency variables best predict performance during EM residency. To evaluate which pre-residency variables best correlated with an applicant's performance during residency. This was a retrospective multicenter sample of all residents in the three most recent graduating classes from nine participating EM residency programs.
External Service and Affiliations
  • American College of Emergency Physicians : Member
  • Society of American Emergency Medicine : Member
  • Medical Society of Delaware : Member
  • Delaware Academy of Medicine : Member