Page 37 - Demo

Those purchasing naloxone in Delaware will undergo a short training to understand how to administer the medication or they can even attend a community training session if they desire. Naloxone can then be administered quickly by family and friends to those that may have overdosed on opioids while also administering rescue breathing/CPR if needed and waiting for emergency responders to arrive and continue care. 
| Pharmacy Services 1. Sun EC, Dixit A, Humphrey K, et al. Association between concurrent use of prescription opioids and
benzodiazepines and overdose: retrospective analysis. BMJ. 2017;356:j760
2. FDA Drug Safety Communication: FDA warns about serious risks and death when combining opioid pain or cough medicines with benzodiazepines; requires its strongest warning. U.S. Food and Drug Administration. Accessed 13 February 2018. Available at: https://www.fda.gov/Drugs/DrugSafety/ucm518473.htm
3. Abbasi Jennifer. VHA Initiative Reduces Risky Opioid Prescribing. JAMA. 2017;317(8):797. doi:10.1001/ jama.2017.1087
4. Jones CM, McAninch JK. Emergency Department Visits and Overdose Deaths From Combined Use of Opioids and Benzodiazepines. Am J Prev Med 2015; 49(4):493-501.
5. Park TW, Saitz R, Ganoczy D, et al. Benzodiazepine prescribing patterns and deaths from drug overdose among US veterans receiving opioid analgesics:case-cohort study. BMJ 2015;350:h2698
6. Lexi-Drugs. Lexi-Comp Online. Lexi-Comp, Inc. Accessed 21 February 2018. Available at https://online.lexi. com/lco/action/home.
7. Narcan Nasal Spray. Adapt Pharma, Inc. Accessed 21 February 2018. Available at https://www.narcan. com/availability.
8. Opioid Addiction Medications in Patients Taking Benzodiazepines or CNS Depressants: Drug Safety Communication - Careful Medication Management Can Reduce Risks. U.S. Food and Drug Administra- tion. Accessed 11 March 2018. Available at https://www.fda.gov/Safety/MedWatch/SafetyInformation/ SafetyAlertsforHumanMedicalProducts/ucm576755.htm?elqTrackId=e65014b0f99945b087eaca49bf2c- 9d77&elq=9f859a946b884b45bb29a278224822d3&elqaid=531&elqat=1&elqCampaignId=191
References
Formulary Update
| March 2018
Medication – Generic/Brand Name
Balanced Electrolyte Intravenous Solution/ Isolyte S
Eltrombopag/Promacta
Gemtuzumab ozogamicin injection/Mylotarg
Rituximab hyaluronidase injection/ Rituxan Hycela
Strength/Size
1000 mL bag
25 mg & 75 mg tablets
4.5 mg vial
1,400 mg & 1,600 mg vials
Use/Indication
IV fluid resuscitation
Treatment of severe aplastic anemia, chronic hepatitis C infection-associated thrombo- cytopenia & chronic immune thrombocytopenia.
Newly diagnosed, relapsed or refractory acute myeloid leukemia.
Treatment of chronic lymphocytic leukemia, diffuse large B-cell lymphoma & follicular lymphoma.
Deleted because of lack of use Product formulation is unavailable The 15-gram tube remains available Deleted because of lack of use Deleted because of lack of use Deleted because of lack of use
Comment
Available from Materials Distribution Storeroom (when there is no national shortage)
Prescribing restricted to hematologists & oncologists
Prescribing restricted to hematologists & oncologists
• Prescribing restricted to hematologists & oncologists
• Availability and administration limited to CCHS owned and affiliated outpatient hematology & oncology office practices
Anthralin cream
Ascorbic acid liquid formulations
Betamethasone dipropionate ointment 0.05% 45-gram tube Calcium gluconate ophthalmic solution
Gentamicin ophthalmic ointment
Hydrocortisone rectal enema
FOCUS • MAY 2018 35
ADDITIONS DELETION